The longest lived laboratory mouse ever was a growth hormone receptor knockout mouse which lived to approximately 1,800 days old in the lab of Andrzej Bartke at Southern Illinois University. The maximum for normal B6 mice under ideal conditions is 1200 days.

In order for a mouse to live for 2,500 days, it is highly likely that a major breakthrough in rejuvenation of mammalian organisms will have to be achieved, and so this achievement would likely have significant implications for humanity.