What is the source of COVID-19 (SARS-CoV-2)?

When a novel coronavirus was first identified in late 2019, the assumption was that, like most epidemics, it was of a zoonotic source. A few studies, including one published in the prestigious Nature magazine, concluded that the virus is not a laboratory construct. Today, claiming a non-zoonotic origin is widely considered a conspiracy theory, and indeed many such claims are easily refutable without requiring probabilistic inference. However, the possibility of a lab escape does require serious examination, especially when considering the proximity of the source to a major coronavirus lab and several unusual findings in the genome of SARS-CoV-2. Due to the complexities of weighing an unlikely lab origin against findings that are unlikely for a zoonotic source, a probabilistic analysis is needed.

This analysis is part of the Rootclaim $100,000 challenge, open to anyone who disagrees with our calculated conclusion. Read more.